Regen Medical specialises in wound healing within the regenerative field. Part of the Joint Operations family, our dedicated team supports its customers within the burns, wound healing, plastics and regenerative fields.

Experts in allograft, Regen Medical are excited to be offering a ground-breaking product portfolio throughout the UK, including products from MiMedx®

MiMedx is a leading biopharmaceutical company developing and marketing regenerative and therapeutic biologics including Epifix®

The EpiFix® dehydrated Human Amnion/Chorion Membrane (dHACM) Allograft from MiMedx is a minimally manipulated natural human amniotic membrane that provides a scaffold for cellular ingrowth, modulates inflammation and reduces scar tissue formation for enhanced healing. An amnion/chorion membrane allograft for homologous use in acute and chronic wound care.

Peer-reviewed publications have demonstrated that PURION processed dHACM recruits stem cells, promotes migration and modulates stem cell activity in vitro and in vivo compared to appropriate controls. EpiFix contains a large and diverse array of 285 regulatory proteins, including growth factors, cytokines, and chemokines that are known to be therapeutic regulators of inflammation, angiogenesis and wound healing.

In a recently published Level 1 study examining the efficacy of EpiFix in conjunction with Standard of Care (SOC) for the treatment of Diabetic Foot Ulcers (DFUs), it was reported that EpiFix demonstrates higher healing rates with a superior wound healing trajectory in a heterogeneous patient population compared with SOC alone (control).


EpiFix Demonstrated Superior Wound Healing at 12 weeks vs. SOC


Level 1 Evidence:

  • Study participants receiving weekly EpiFix with SOC* exhibited superior wound healing compared to treatment with SOC alone.
  • EpiFix patients were significantly more likely to completely heal compared to control.
  • Cox regression analysis showed subjects treated with EpiFix were more than twice as likely to heal completely within 12 weeks as thiose not receiving EpiFix, after adjusted for covariates such as wound size, wound location, history, etc.
  • ITT analysis reduces bias that may occur when factors such as protocol deviation and non-compliance are excluded from the analysis. PP data more closely reflect expected clinical practice outcomes on patients who are compliant with study protocol.

*SOC = alginate dressings, absorbent non -adhesive hydropolymer secondary dressings, gauze, and an offloading devize (cam walker, offloading boot, shoe, or complete contact cast) as indicated.


90+% Healed

90+% Healing Rates in Diabetic Foot Ulcers at 6 weeks1 (Single Center RCT)

81% Healed

81% Complete Healing in Diabetic Foot Ulcers at 12 weeks2 (Multicenter RCT)

71% Healed

71% Complete Healing in Venous Leg Ulcers at 16 weeks3 (Multicenter RCT)

285 regulatory proteins

285 Regulatory Proteins are Contained in EpiFix4-6

40 plus publications

40+ Clinical and Scientific Publications


EpiFix Logo

Dehydrated human amnion/chorion membrane allograft
Purion Logo

EpiFix is processed using the PURION process, a unique approach that provides an easy to use allograft stored at ambient conditions.
MiMedx Logo

1. Tettelbach W, Cazzell S, Reyzelman AM, Sigal F, Caporusso JM, Agnew PS.  A confirmatory study on the efficacy of dehydrated human amnion/chorion membrane dHACM allograft in the management of diabetic foot ulcers: A prospective, multicentre, randomised, controlled study of 110 patients from 14 wound clinics.  Int Wound J. 2018;1-11.
Patents and patents pending see:  Epifix®, PURION
®, and MiMedx® are registered U.S. trademarks of MiMedx Group, Inc. 1775 West Oak Commons Court NE, Marietta, GA 30062 2018 MiMedx Group, Inc. All Rights Reserved. EP539.001
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